Invention Grant
- Patent Title: Radiolabeled cannabinoid-1 receptor modulators
- Patent Title (中): 放射性标记的大麻素-1受体调节剂
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Application No.: US10559228Application Date: 2004-06-25
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Publication No.: US07754188B2Publication Date: 2010-07-13
- Inventor: H. Donald Burns , Alex M. Chen , Raymond E. Gibson , Mark T. Goulet , William K. Hagmann , Terence G. Hamill , James P. Jewell , Linus S. Lin , Ping Liu , Andrey V. Peresypkin
- Applicant: H. Donald Burns , Alex M. Chen , Raymond E. Gibson , Mark T. Goulet , William K. Hagmann , Terence G. Hamill , James P. Jewell , Linus S. Lin , Ping Liu , Andrey V. Peresypkin
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Baerbel R. Brown; Catherine D. Fitch; John C. Todaro
- International Application: PCT/US2004/020233 WO 20040625
- International Announcement: WO2005/009479 WO 20050203
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14
Abstract:
The present invention relates to particular radiolabeled Cannabinoid-1 (CB1) receptor modulators, and methods of using these modulators for labeling and diagnostic imaging of Cannabinoid-1 receptors in mammals, particularly humans. In addition, intermediates useful for the synthesis of the radiolabeled Cannabinoid-1 receptor modulators are also disclosed, as well as the processes for synthesizing the radiolabeled Cannabinoid-1 receptor modulators. Still further, formulations of the radiolabeled Cannabinoid-1 receptor compounds are described.
Public/Granted literature
- US20060115425A1 Substituted amides Public/Granted day:2006-06-01
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