Invention Grant
- Patent Title: Methods of controlling cell differentiation and growth using a fusion protein and a drug
- Patent Title (中): 使用融合蛋白和药物控制细胞分化和生长的方法
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Application No.: US09582916Application Date: 1999-01-07
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Publication No.: US07754202B1Publication Date: 2010-07-13
- Inventor: Carl Anthony Blau , David M. Spencer
- Applicant: Carl Anthony Blau , David M. Spencer
- Applicant Address: US CA Palo Alto US WA Seattle
- Assignee: Stanford University,University of Washington
- Current Assignee: Stanford University,University of Washington
- Current Assignee Address: US CA Palo Alto US WA Seattle
- Agency: Nixon Peabody LLP
- International Application: PCT/US99/00348 WO 19990107
- International Announcement: WO99/34836 WO 19990715
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N5/00 ; C12N15/63
Abstract:
This invention involves methods and materials for conferring a direct proliferative advantage on a genetically modified subpopulation of cells. Selection is then accomplished by exerting a positive selective stimulus on the engineered cells rather than a negative pressure on nonengineered cells.
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