Invention Grant
- Patent Title: Method of judging inflammatory disease
- Patent Title (中): 炎症性疾病的诊断方法
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Application No.: US10523723Application Date: 2003-08-08
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Publication No.: US07754422B2Publication Date: 2010-07-13
- Inventor: Toshihiro Tanaka , Yozo Ohnishi , Koichi Ozaki , Aritoshi Iida , Yusuke Nakamura , Masatsugu Hori
- Applicant: Toshihiro Tanaka , Yozo Ohnishi , Koichi Ozaki , Aritoshi Iida , Yusuke Nakamura , Masatsugu Hori
- Applicant Address: JP Saitama
- Assignee: Riken
- Current Assignee: Riken
- Current Assignee Address: JP Saitama
- Agency: Greenblum & Bernstein, P.L.C.
- Priority: JP2002-231532 20020808
- International Application: PCT/JP03/10131 WO 20030808
- International Announcement: WO2004/015100 WO 20040219
- Main IPC: C12Q1/68
- IPC: C12Q1/68

Abstract:
The object of the present invention is to determine inflammatory diseases such as myocardial infarction by identifying single nucleotide polymorphisms (SNPs) associated with myocardial infarction and utilizing these SNPs. The present invention provides a method for determining an inflammatory disease, which comprises detecting at least one gene polymorphism existing in at least one gene selected from the group consisting of a lymphotoxin-α (LT-α) gene, an I Kappa B-like (IKBL) gene, and a BAT1 gene; an oligonucleotide used in said method; a kit for diagnosing an inflammatory disease which comprises said oligonucleotide; and use thereof. The present invention further provides a method for treating an inflammatory disease; and a method for screening for a therapeutic agent for an inflammatory disease.
Public/Granted literature
- US20060147920A1 Method of judging inflammatory disease Public/Granted day:2006-07-06
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