Invention Grant
- Patent Title: Stabilized FGF formulations containing reducing agents
- Patent Title (中): 含有还原剂的稳定的FGF制剂
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Application No.: US09944930Application Date: 2001-08-31
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Publication No.: US07754686B2Publication Date: 2010-07-13
- Inventor: Robert V. Hageman , Bret A. Shirley , Kamaljit K. Bajwa
- Applicant: Robert V. Hageman , Bret A. Shirley , Kamaljit K. Bajwa
- Applicant Address: US CA Emeryville
- Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee Address: US CA Emeryville
- Agency: Alston & Bird LLP
- Main IPC: A61K38/16
- IPC: A61K38/16 ; A61K38/18 ; C07K14/435 ; C07K14/50
Abstract:
Stabilized FGF compositions are provided. The compositions comprise FGF or variant thereof and at least one reducing agent in an amount sufficient to inhibit FGF oxidation. Methods for increasing stability of FGF or variant thereof in a liquid or lyophilized composition and for increasing storage stability of such a composition are also provided.
Public/Granted literature
- US20080293624A1 Stabilized FGF formulations containing reducing agents Public/Granted day:2008-11-27
Information query
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