Invention Grant
- Patent Title: Bis-aryl amide compounds and methods of use
- Patent Title (中): 双芳基酰胺化合物及其使用方法
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Application No.: US11503551Application Date: 2006-08-11
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Publication No.: US07754717B2Publication Date: 2010-07-13
- Inventor: Erin F. Dimauro , Jean E. Bemis , Stuart C. Chaffee , Ning Chen , Essa Hu , Roxanne Kunz , Matthew W. Martin , David C. McGowan , Shannon Rumfelt
- Applicant: Erin F. Dimauro , Jean E. Bemis , Stuart C. Chaffee , Ning Chen , Essa Hu , Roxanne Kunz , Matthew W. Martin , David C. McGowan , Shannon Rumfelt
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent G. Prabhakar Reddy
- Main IPC: A01N43/60
- IPC: A01N43/60 ; A01N43/54 ; A01N43/42 ; A61K31/495 ; A61K31/50 ; A61K31/501 ; A61K31/4965 ; A61K31/51 ; A61K31/47 ; C07D239/42 ; C07D401/04 ; C07D237/30 ; C07D401/00
Abstract:
The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including autoimmune disease and inflammation. In one embodiment, the compounds have a general Formula I wherein A1, A2, A3, A4, L, R1, R2 and R3 are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of the present invention, methods of use such as treatment of Lck and/or c-Kit kinase mediated diseases by administering the compounds of the invention, or compositions including one or more compounds of the invention, and intermediates and processes useful for the preparation of compounds of the present invention.
Public/Granted literature
- US20070072862A1 Bis-aryl amide compounds and methods of use Public/Granted day:2007-03-29
Information query
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