Invention Grant
- Patent Title: Crystalline topotecan hydrochloride product and process for making the same
- Patent Title (中): 结晶托泊替康盐酸盐产品及其制备方法
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Application No.: US10578660Application Date: 2004-11-12
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Publication No.: US07754733B2Publication Date: 2010-07-13
- Inventor: Philip C. Dell'orco , Ann Marie Diederich , Qiaogong Su , Jeffery Lee Wood
- Applicant: Philip C. Dell'orco , Ann Marie Diederich , Qiaogong Su , Jeffery Lee Wood
- Applicant Address: US PA Philadelphia
- Assignee: GlaxoSmithKline LLC
- Current Assignee: GlaxoSmithKline LLC
- Current Assignee Address: US PA Philadelphia
- Agent Kathryn L. Sieburth; Lorraine Ling
- International Application: PCT/US2004/037626 WO 20041112
- International Announcement: WO2005/046608 WO 20050526
- Main IPC: C07D491/22
- IPC: C07D491/22 ; A61K31/4745
Abstract:
Disclosed is a novel crystalline form of topotecan monohydrochloride pentahydrate, which is a pentahydrate of 10-[(dimethylamino)methyl]4-ethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H, 12H)dione monohydrochloride, corresponding pharmaceutical compositions, methods preparation and/or use thereof to treat anti-viral and/or cancer related diseases.
Public/Granted literature
- US20070117832A1 Novel compound, corresponding compositons, preparation and/or treatment methods Public/Granted day:2007-05-24
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