Invention Grant
- Patent Title: Modulators of CFTR
- Patent Title (中): CFTR调制器
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Application No.: US12117948Application Date: 2008-05-09
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Publication No.: US07754739B2Publication Date: 2010-07-13
- Inventor: Sara S. Hadida Ruah , Mark Miller , Brian Bear , Jinglan Zhou , Jason McCartney , Peter Grootenhuis
- Applicant: Sara S. Hadida Ruah , Mark Miller , Brian Bear , Jinglan Zhou , Jason McCartney , Peter Grootenhuis
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Michael J. Diverdi
- Main IPC: A61K31/4418
- IPC: A61K31/4418 ; A61K31/443 ; C07D405/02 ; C07D213/72
Abstract:
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Public/Granted literature
- US20080286204A1 MODULATORS OF CFTR Public/Granted day:2008-11-20
Information query
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