Invention Grant
US07754740B2 1H-indole-3-carboxylic acid derivatives and their use as PPAR agonists
失效
1H-吲哚-3-羧酸衍生物及其作为PPAR激动剂的用途
- Patent Title: 1H-indole-3-carboxylic acid derivatives and their use as PPAR agonists
- Patent Title (中): 1H-吲哚-3-羧酸衍生物及其作为PPAR激动剂的用途
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Application No.: US11813922Application Date: 2005-12-17
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Publication No.: US07754740B2Publication Date: 2010-07-13
- Inventor: Nathalie Adje , Didier Roche , Stéphane Yvon
- Applicant: Nathalie Adje , Didier Roche , Stéphane Yvon
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: FR0500422 20050114
- International Application: PCT/EP2005/013634 WO 20051217
- International Announcement: WO2006/074789 WO 20060720
- Main IPC: A61K31/404
- IPC: A61K31/404 ; A61K31/4439 ; C07D209/12 ; C07D401/12
Abstract:
Compounds of the formula (1): in which A, R1, R2 and R3 are as defined in the description, the processes for the preparation of these compounds, the uses thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, and the pharmaceutical compositions comprising them.
Public/Granted literature
- US20080114034A1 1H-Indole-3-Carboxylic Acid Derivatives And Their Use As Ppar Agonists Public/Granted day:2008-05-15
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