Invention Grant
- Patent Title: Compounds for the treatment of AIDS and other viral diseases
- Patent Title (中): 用于治疗艾滋病和其他病毒性疾病的化合物
-
Application No.: US11362567Application Date: 2006-02-23
-
Publication No.: US07754771B2Publication Date: 2010-07-13
- Inventor: Eliahu Kaplan
- Applicant: Eliahu Kaplan
- Applicant Address: IL Tel-Aviv
- Assignee: Novaremed Limited
- Current Assignee: Novaremed Limited
- Current Assignee Address: IL Tel-Aviv
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Agent Ivor R. Elrifi; Jennifer L. Loebach
- Main IPC: A61K31/135
- IPC: A61K31/135 ; C07C235/34

Abstract:
The present invention provides methods for treating Acquired Immunodeficiency Syndrome (AIDS) and other viral diseases and Human Immunodeficiency Virus (HIV) related infections by administering one or more compounds of formula I: wherein: the dotted line represents a single or a double bond; and R1 and R2 are the same or different and independently of each other represent —CH2OH, —CH2OR4, —CH(OH)CH3, —CH(OR4)CH3 or a group represented by the formula: or salts or hydrates thereof in a carrier which minimizes micellar formation or van der Waals attraction of molecules of said compound. The invention also provides S enantiomeric forms of such compounds which possess the ability to inhibit cell growth whilst being of low toxicity to such cells and methods of making such compounds.
Public/Granted literature
Information query