Invention Grant
- Patent Title: Non-endogenous, constitutively activated human serotonin receptors and small molecule modulators thereof
- Patent Title (中): 非内源性,组成型激活的人血清素受体及其小分子调节剂
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Application No.: US12051754Application Date: 2008-03-19
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Publication No.: US07754866B2Publication Date: 2010-07-13
- Inventor: Dominic P. Behan , Derek T. Chalmers , Chen W. Liaw , Joseph F. Russo , William J. Thomsen
- Applicant: Dominic P. Behan , Derek T. Chalmers , Chen W. Liaw , Joseph F. Russo , William J. Thomsen
- Applicant Address: US CA San Diego
- Assignee: Arena Pharmaceuticals, Inc.
- Current Assignee: Arena Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Bozicevic, Field & Francis LLP
- Agent David C. Scherer
- Main IPC: C07H21/04
- IPC: C07H21/04

Abstract:
Disclosed herein are non-endogenous, constitutively activated forms of the human 5-HT2A and human 5-HT2C receptors and uses of such receptors to screen candidate compounds. Further disclosed herein are candidate compounds identified by the screening method which act at the 5HT2A receptors. Yet further disclosed is a new class of compounds which act at the 5HT2A receptors.
Public/Granted literature
- US20090076254A1 NON-ENDOGENOUS, CONSTITUTIVELY ACTIVATED HUMAN SEROTONIN RECEPTORS AND SMALL MOLECULE MODULATORS THEREOF Public/Granted day:2009-03-19
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