Invention Grant
US07754872B2 Liposomal phosphodiester, phophorothioate, and p-ethoxy oligonucleotides
失效
脂质体磷酸二酯，磷酸二酯和对乙氧基寡核苷酸
- Patent Title: Liposomal phosphodiester, phophorothioate, and p-ethoxy oligonucleotides
- Patent Title (中): 脂质体磷酸二酯，磷酸二酯和对乙氧基寡核苷酸
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Application No.: US11674563Application Date: 2007-02-13
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Publication No.: US07754872B2Publication Date: 2010-07-13
- Inventor: Gabriel Lopez-Berestein , Ana Maria Tari
- Applicant: Gabriel Lopez-Berestein , Ana Maria Tari
- Applicant Address: US TX Austin
- Assignee: Board of Regents, the University of Texas System
- Current Assignee: Board of Regents, the University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Fulbright & Jaworski L.L.P.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K9/127
Abstract:
An improved delivery system for antisense oligonucleotides involves a liposomal composition, comprising a liposome which consists essentially of neutral phospholipids and an antisense oligonucleotide that is entrapped in the liposome and is selected from the group consisting of phosphodiester oligonucleotides, phosphorothioate oligonucleotides, and p-ethoxy oligonucleotides.
Public/Granted literature
- US20070202157A1 Liposomal Phosphodiester, Phosphorothioate, and p-Ethoxy Oligonucleotides Public/Granted day:2007-08-30
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