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US07754892B2 Processes for the preparation of N-(2-acetyl-4,6-dimethylphenyl)-3-{[(3,4 dimethyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxamide 失效
制备N-(2-乙酰基-4,6-二甲基苯基)-3 - {[(3,4-二甲基-5-异恶唑基)氨基]磺酰基} -2-噻吩甲酰胺的方法

  • Patent Title: Processes for the preparation of N-(2-acetyl-4,6-dimethylphenyl)-3-{[(3,4 dimethyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxamide
  • Patent Title (中): 制备N-(2-乙酰基-4,6-二甲基苯基)-3 - {[(3,4-二甲基-5-异恶唑基)氨基]磺酰基} -2-噻吩甲酰胺的方法
  • Application No.: US11890201
    Application Date: 2007-08-03
  • Publication No.: US07754892B2
    Publication Date: 2010-07-13
  • Inventor: John F. Reichwein
  • Applicant: John F. Reichwein
  • Applicant Address: US NY New York
  • Assignee: Encysive Pharmaceuticals, Inc.
  • Current Assignee: Encysive Pharmaceuticals, Inc.
  • Current Assignee Address: US NY New York
  • Agent Gregg C. Benson; Robert T. Ronau
  • Main IPC: C07D413/12
  • IPC: C07D413/12 C07D333/38
Processes for the preparation of N-(2-acetyl-4,6-dimethylphenyl)-3-{[(3,4 dimethyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxamide
Abstract:
Provided are processes for the preparation of N-(2-acetyl-4,6-dimethylphenyl)-3-{[(3,4 dimethyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxamide, a compound useful for the treatment of endothelin-mediated disorders.
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