Mechanisms for adjusting direction of data flow between input/output (I/O) bridges and I/O hubs based on real time traffic levels are provided. The mechanisms of the illustrative embodiments provide firmware and/or hardware for monitoring data flow through an I/O bridge loop and corresponding I/O hub in order to determine if a condition exists requiring reassignment of the direction each I/O bridge sends its data. In particular, the firmware/hardware determines whether a current traffic condition through the I/O bridges and I/O hub meets criteria indicative of one pathway through the I/O bridge loop being over-utilized while another pathway through the I/O bridge loop is under-utilized. If it is determined that such a condition exists, the configuration of the I/O bridges may be automatically modified to reassign which pathway is utilized by the I/O bridge in sending/receiving I/O data traffic through the I/O bridge loop.