Invention Grant
- Patent Title: Assay method for alzheimer's disease
- Patent Title (中): 阿尔茨海默病的测定方法
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Application No.: US10486908Application Date: 2002-08-16
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Publication No.: US07771722B2Publication Date: 2010-08-10
- Inventor: David M. Holtzman , Ronald DeMattos , Kelly R. Bales , David J. Cummins , Steven M. Paul
- Applicant: David M. Holtzman , Ronald DeMattos , Kelly R. Bales , David J. Cummins , Steven M. Paul
- Applicant Address: US IN Indianapolis US MO St. Louis
- Assignee: Eli Lilly and Company,Washington University
- Current Assignee: Eli Lilly and Company,Washington University
- Current Assignee Address: US IN Indianapolis US MO St. Louis
- Agency: McAndrews, Held & Malloy, Ltd.
- International Application: PCT/US02/26321 WO 20020816
- International Announcement: WO03/015617 WO 20030227
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K49/00

Abstract:
A diagnostic test for preclinical and clinical Alzheimer's disease is based on plasma levels of Aβ40, Aβ42, their ratio, or their rate of entry following administration of antibodies that sequester Aβ. Alterations of any of these parameters from control values identifies preclinical or clinical Alzheimer's disease.
Public/Granted literature
- US20040248197A1 Assay method for alzheimer's disease Public/Granted day:2004-12-09
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