Invention Grant
US07771940B2 Methods of detecting a plurality of sequence specific DNA binding proteins with oligonucleotide detection duplexes
失效
用寡核苷酸检测双链体检测多个序列特异性DNA结合蛋白的方法
- Patent Title: Methods of detecting a plurality of sequence specific DNA binding proteins with oligonucleotide detection duplexes
- Patent Title (中): 用寡核苷酸检测双链体检测多个序列特异性DNA结合蛋白的方法
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Application No.: US11549830Application Date: 2006-10-16
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Publication No.: US07771940B2Publication Date: 2010-08-10
- Inventor: Peter A. Clausen , David P. Carlson , James G. Lazar
- Applicant: Peter A. Clausen , David P. Carlson , James G. Lazar
- Applicant Address: US MD Ijamsville
- Assignee: Marligen Biosciences, Inc.
- Current Assignee: Marligen Biosciences, Inc.
- Current Assignee Address: US MD Ijamsville
- Agency: Perkins Coie LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/53
Abstract:
Compositions and methods are provided for detecting and measuring DNA-binding proteins. The compositions and methods permit the simultaneous or near-simultaneous detection of multiple DNA-binding proteins in a multiplex or array format, and can be used to generate profiles of DNA binding activity by proteins, specifically, transcription factors. Multiple protein-DNA binding events in a single sample may be detected and quantitated in a high-throughput format.
Public/Granted literature
- US20090208927A1 Methods of detecting sequence-specific DNA binding proteins Public/Granted day:2009-08-20
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