Invention Grant
- Patent Title: Enhanced expression and stability regions
- Patent Title (中): 增强表达和稳定性区域
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Application No.: US12132846Application Date: 2008-06-04
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Publication No.: US07771997B2Publication Date: 2010-08-10
- Inventor: Gang Chen , Robert Babb , James P. Fandl
- Applicant: Gang Chen , Robert Babb , James P. Fandl
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agent Kevin J. Pobursky; Tor E. Smeland, Esq.; Valeta Gregg, Esq.
- Main IPC: C12N5/10
- IPC: C12N5/10
Abstract:
Expression-enhancing nucleotide sequences for expression in eukaryotic systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Enhanced expression and stability regions (EESYRs) are provided for expression of a gene of interest in a eukaryotic cell. Chromosomal loci, sequences, and vectors are provided for enhanced and stable expression of genes in eukaryotic cells.
Public/Granted literature
- US20090124005A1 Enhanced Expression and Stability Regions Public/Granted day:2009-05-14
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