Invention Grant
US07772259B2 1,2,4-Oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease
有权
1,2,4-恶二唑苯甲酸化合物及其用于无味抑制和治疗疾病的用途
- Patent Title: 1,2,4-Oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease
- Patent Title (中): 1,2,4-恶二唑苯甲酸化合物及其用于无味抑制和治疗疾病的用途
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Application No.: US11042652Application Date: 2005-01-24
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Publication No.: US07772259B2Publication Date: 2010-08-10
- Inventor: Gary Mitchell Karp , Seongwoo Hwang , Guangming Chen , Neil Gregory Almstead
- Applicant: Gary Mitchell Karp , Seongwoo Hwang , Guangming Chen , Neil Gregory Almstead
- Applicant Address: US NJ South Plainfield
- Assignee: PTC Therapeutics, Inc.
- Current Assignee: PTC Therapeutics, Inc.
- Current Assignee Address: US NJ South Plainfield
- Agency: Jones Day
- Main IPC: A61K31/41
- IPC: A61K31/41 ; C07D271/06
Abstract:
Novel 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising an 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.
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