Invention Grant
- Patent Title: Internalizing anti-CD74 antibodies and methods of use
- Patent Title (中): 内化抗CD74抗体及其使用方法
-
Application No.: US11867775Application Date: 2007-10-05
-
Publication No.: US07772373B2Publication Date: 2010-08-10
- Inventor: Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- Applicant: Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- Applicant Address: US NJ Morris Plains
- Assignee: Immunomedics, Inc.
- Current Assignee: Immunomedics, Inc.
- Current Assignee Address: US NJ Morris Plains
- Agent Richard A. Nakashima
- Main IPC: C07K16/00
- IPC: C07K16/00
Abstract:
The present invention provides humanized, chimeric and human anti-CD74 antibodies, CD74 antibody fusion proteins, immunoconjugates, vaccines and bispecific that bind to CD74, the major histocompatibility complex (MHC) class-II invariant chain, Ii, which is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies, other malignancies in which the cells are reactive with CD74, and autoimmune diseases, and methods of treatment and diagnosis.
Public/Granted literature
- US20080166342A1 INTERNALIZING ANTI-CD74 ANTIBODIES AND METHODS OF USE Public/Granted day:2008-07-10
Information query
