Invention Grant
- Patent Title: C-glycoside derivatives and salts thereof
- Patent Title (中): C-糖苷衍生物及其盐
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Application No.: US11710434Application Date: 2007-02-26
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Publication No.: US07772407B2Publication Date: 2010-08-10
- Inventor: Masakazu Imamura , Takeshi Murakami , Ryota Shiraki , Kazuhiro Ikegai , Takashi Sugane , Fumiyoshi Iwasaki , Eiji Kurosaki , Hiroshi Tomiyama , Atsushi Noda , Kayoko Kitta , Yoshinori Kobayashi
- Applicant: Masakazu Imamura , Takeshi Murakami , Ryota Shiraki , Kazuhiro Ikegai , Takashi Sugane , Fumiyoshi Iwasaki , Eiji Kurosaki , Hiroshi Tomiyama , Atsushi Noda , Kayoko Kitta , Yoshinori Kobayashi
- Applicant Address: JP Tokyo JP Nagano
- Assignee: Astellas Pharma Inc.,Kotobuki Pharmaceuticals Co., Ltd.
- Current Assignee: Astellas Pharma Inc.,Kotobuki Pharmaceuticals Co., Ltd.
- Current Assignee Address: JP Tokyo JP Nagano
- Agency: Sughrue Mion, PLLC
- Priority: JP2003-070297 20030314
- Main IPC: A61K31/7034
- IPC: A61K31/7034 ; A61K31/381 ; C07H7/04 ; C07D333/34 ; C07D495/00
Abstract:
The present invention provides C-glycoside derivatives and salts thereof, wherein B ring is bonded to A ring via —X— and A ring is directly bonded to the glucose residue, and it is usable as a Na+-glucose cotransporter inhibitor, especially for a therapeutic and/or preventive agent for diabetes such as insulin-dependent diabetes (type 1 diabetes) and insulin-independent diabetes (type 2 diabetes), as well as diabetes related diseases such as an insulin-resistant diseases and obesity.
Public/Granted literature
- US20070161787A1 C-glycoside derivatives and salts thereof Public/Granted day:2007-07-12
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