Invention Grant
US07780982B2 Biodegradable hyaluronic acid derivative and biodegradable polymeric micelle composition
有权
可生物降解的透明质酸衍生物和可生物降解的聚合胶束组合物
- Patent Title: Biodegradable hyaluronic acid derivative and biodegradable polymeric micelle composition
- Patent Title (中): 可生物降解的透明质酸衍生物和可生物降解的聚合胶束组合物
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Application No.: US10992387Application Date: 2004-11-18
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Publication No.: US07780982B2Publication Date: 2010-08-24
- Inventor: Jui-Hsiang Chen , Bin-Hong Tsai , Hsuen-Tseng Chang , Muh-Lan Chen , Yu-Hua Chen , Shu-Hua Jan , Mei-Jung Liu
- Applicant: Jui-Hsiang Chen , Bin-Hong Tsai , Hsuen-Tseng Chang , Muh-Lan Chen , Yu-Hua Chen , Shu-Hua Jan , Mei-Jung Liu
- Applicant Address: TW Chutung, Hsinchu
- Assignee: Industrial Technology Research Instittute
- Current Assignee: Industrial Technology Research Instittute
- Current Assignee Address: TW Chutung, Hsinchu
- Agency: Thomas, Kayden, Horstemeyer & Risley
- Priority: GB0328168.0 20031204
- Main IPC: A61K9/127
- IPC: A61K9/127
Abstract:
A biodegradable hyaluronic acid derivative comprising a modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C═O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group or a prepolymer, and p is an integer of 1 to 4. The biodegradable hyaluronic acid derivative when dissolved in a hydrophilic medium can form micelles and can be used to entrap a pharmaceutically active or bioactive molecule.
Public/Granted literature
- US20050123505A1 Biodegradable hyaluronic acid derivative and biodegradable polymeric micelle composition Public/Granted day:2005-06-09
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