Invention Grant
US07781161B2 Genomic screen for epigenetically silenced tumor suppressor genes
有权
表观遗传学沉默肿瘤抑制基因的基因组筛选
- Patent Title: Genomic screen for epigenetically silenced tumor suppressor genes
- Patent Title (中): 表观遗传学沉默肿瘤抑制基因的基因组筛选
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Application No.: US10383864Application Date: 2003-03-07
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Publication No.: US07781161B2Publication Date: 2010-08-24
- Inventor: David Sidransky , Stephen B Baylin , James Herman , Hiromu Suzuki
- Applicant: David Sidransky , Stephen B Baylin , James Herman , Hiromu Suzuki
- Applicant Address: US MD Baltimore
- Assignee: The Johns Hopkins University School of Medicine
- Current Assignee: The Johns Hopkins University School of Medicine
- Current Assignee Address: US MD Baltimore
- Agency: DLA Piper LLP (US)
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/02 ; C07H21/04
Abstract:
Methods of genomic screening to identify epigenetically silenced genes, including epigenetically silenced tumor suppressor genes are provided. Also provided are methods of detecting a cancer, for example, an esophageal squamous cell carcinoma or a head and neck squamous cell carcinoma, as are methods of treating a subject having such a cancer.
Public/Granted literature
- US20040081976A1 Genomic screen for epigenetically silenced tumor suppressor genes Public/Granted day:2004-04-29
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