Invention Grant
- Patent Title: Screening methods using normal human liver cell line
- Patent Title (中): 使用正常人肝细胞系筛选方法
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Application No.: US11335352Application Date: 2006-01-19
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Publication No.: US07781186B2Publication Date: 2010-08-24
- Inventor: Jetsumon Prachumsri , Nongnuch Yimamnuaychok
- Applicant: Jetsumon Prachumsri , Nongnuch Yimamnuaychok
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Secretary of the Army
- Current Assignee: The United States of America as represented by the Secretary of the Army
- Current Assignee Address: US DC Washington
- Agent Elizabeth Arwine
- Main IPC: C12Q1/18
- IPC: C12Q1/18 ; C12N5/071
Abstract:
In this application is described the establishment and maintenance of a normal human hepatocyte cell line able to support complete development of malaria parasite development in vitro. The cell line can be used in methods for screening compounds affecting normal human liver cells or normal human cells infected with malaria parasites, measuring uptake of drugs or chemicals into normal human liver cells, and measuring metabolism of a drug in a normal human liver cell. Other advantages and uses of the cell line are also described.
Public/Granted literature
- US20060160216A1 Human liver cell line Public/Granted day:2006-07-20
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