Invention Grant
US07781451B2 Thiazolopyridine derivatives, pharmaceut ical conditions containing them and methods of treating glucokinase mediated conditions
失效
噻唑并吡啶衍生物,含有它们的药物条件和治疗葡糖激酶介导的病症的方法
- Patent Title: Thiazolopyridine derivatives, pharmaceut ical conditions containing them and methods of treating glucokinase mediated conditions
- Patent Title (中): 噻唑并吡啶衍生物,含有它们的药物条件和治疗葡糖激酶介导的病症的方法
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Application No.: US11547227Application Date: 2005-04-01
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Publication No.: US07781451B2Publication Date: 2010-08-24
- Inventor: Gregory R Bebernitz , Ramesh C Gupta , Vikrant V Jagtap , Appaji B Mandhare , Davinder Tuli
- Applicant: Gregory R Bebernitz , Ramesh C Gupta , Vikrant V Jagtap , Appaji B Mandhare , Davinder Tuli
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Theresa Devlin
- International Application: PCT/EP2005/003454 WO 20050401
- International Announcement: WO2005/095417 WO 20051013
- Main IPC: A61K31/429
- IPC: A61K31/429 ; C07D513/04

Abstract:
The present invention provides compounds of the formula which are activators of glucokinase activity and, thus, may be employed as therapeutic agents for the treatment of glucokinase mediated conditions. Accordingly, the compounds of formula (I) may be employed for the prevention and the treatment of impaired glucose tolerance, Type 2 diabetes and obesity.
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