Invention Grant
- Patent Title: Derivatives of pyridine and quinoline
- Patent Title (中): 吡啶和喹啉的衍生物
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Application No.: US10597095Application Date: 2005-01-11
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Publication No.: US07781458B2Publication Date: 2010-08-24
- Inventor: Juan Carlos Lacal Sanjuán , Joaquin Campos Rosa , Miguel Ángel Gallo Mezo , Antonio Espinosa Úbeda
- Applicant: Juan Carlos Lacal Sanjuán , Joaquin Campos Rosa , Miguel Ángel Gallo Mezo , Antonio Espinosa Úbeda
- Applicant Address: ES Madrid ES Granada
- Assignee: Consejo Superior de Investigaciones Cientificas,Universidad de Granada
- Current Assignee: Consejo Superior de Investigaciones Cientificas,Universidad de Granada
- Current Assignee Address: ES Madrid ES Granada
- Agency: Moore & Van Allen, PLLC
- Agent Tristan A. Fuierer
- Priority: ES200400072 20040114
- International Application: PCT/ES2005/070002 WO 20050111
- International Announcement: WO2005/068429 WO 20050728
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D215/38 ; C07D213/74

Abstract:
The invention provides compounds of formula I blocking phosphorylcholine biosynthesis by means of the selective blocking of the choline kinase enzyme in tumor cells or in cells affected by parasitic infection and therefore being applicable in the treatment of tumors and parasitic diseases or diseases produced by viruses and fungi in animals, including human beings; as well as to a method for preparing the compounds of the invention and certain intermediates of said method.
Public/Granted literature
- US20070185170A1 Derivatives of pyridine and quinoline Public/Granted day:2007-08-09
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