Invention Grant
- Patent Title: Hsp90 family protein inhibitors
- Patent Title (中): Hsp90家族蛋白抑制剂
-
Application No.: US11718079Application Date: 2005-11-09
-
Publication No.: US07781485B2Publication Date: 2010-08-24
- Inventor: Yushi Kitamura , Yutaka Kanda , Takayuki Nakashima
- Applicant: Yushi Kitamura , Yutaka Kanda , Takayuki Nakashima
- Applicant Address: JP Tokyo
- Assignee: Kyowa Hakko Kirin Co., Ltd.
- Current Assignee: Kyowa Hakko Kirin Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Fitzpatrick, Cella, Harper & Scinto
- Priority: JP2004-324480 20041109
- International Application: PCT/JP2005/020519 WO 20051109
- International Announcement: WO2006/051808 WO 20060518
- Main IPC: A61K31/24
- IPC: A61K31/24 ; A61K31/235

Abstract:
The present invention provides Hsp90 family protein inhibitors comprising, as an active ingredient, a benzoic acid derivative represented by General Formula (I): [wherein n represents an integer of 0 to 10; R1 represents substituted or unsubstituted lower alkoxycarbonyl, substituted or unsubstituted aroyl, or the like; R2 represents —NR14R15 (wherein R14 and R15 may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted aralkyl or the like); R3 and R5 may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl or the like; and R4 and R6 may be the same or different and each represents a hydrogen atom, halogen, substituted or unsubstituted lower alkyl or the like] or a prodrug thereof, or a pharmaceutically acceptable salt of said benzoic acid derivative or said prodrug.
Public/Granted literature
- US20070265268A1 Hsp90 Family protein Inhibitors Public/Granted day:2007-11-15
Information query