Invention Grant
US07781594B2 5-(4-methanesulfonyl-phenyl)-thiazole derivatives for the treatment of acute and chronic inflammatory diseases
有权
5-（4-甲磺酰基 - 苯基） - 噻唑衍生物，用于治疗急性和慢性炎性疾病
- Patent Title: 5-(4-methanesulfonyl-phenyl)-thiazole derivatives for the treatment of acute and chronic inflammatory diseases
- Patent Title (中): 5-（4-甲磺酰基 - 苯基） - 噻唑衍生物，用于治疗急性和慢性炎性疾病
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Application No.: US12139661Application Date: 2008-06-16
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Publication No.: US07781594B2Publication Date: 2010-08-24
- Inventor: Victor Rubio Royo , Antonio De La Hera Martinez , Melchor Alvarez De Mon Soto , Ana Munoz Munoz
- Applicant: Victor Rubio Royo , Antonio De La Hera Martinez , Melchor Alvarez De Mon Soto , Ana Munoz Munoz
- Applicant Address: ES Leioa Vizcaya
- Assignee: Faes Farma, S.A.
- Current Assignee: Faes Farma, S.A.
- Current Assignee Address: ES Leioa Vizcaya
- Agency: Intellectual Property Technology Law
- Agent Steven J. Hultquist; Kelly K. Reynolds
- Main IPC: A61K31/426
- IPC: A61K31/426 ; C07D275/03
Abstract:
The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt, prodrug and/or solvate thereof, and to a method for the treatment an acute or chronic inflammatory disease by inhibiting the production of at least one pro-inflammatory cytokine selected from TNF-alpha, IFN-gamma, IL-8 and IL-10, which comprises administering to a patient who needs such treatment a therapeutically effective amount of a compound of formula (I) as defined above.
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