Invention Grant
- Patent Title: Biosensor to determine potassium concentration in human blood serum
- Patent Title (中): 生物传感器测定人血清中的钾浓度
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Application No.: US11691712Application Date: 2007-03-27
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Publication No.: US07790112B2Publication Date: 2010-09-07
- Inventor: Sunkam Vanaja , Mandapati Jayalakshmi , Sunkara Sakunthala Madhavendra , Kaki Rajgopal , Mannepalli Lakshmi Kantam , Sunkara Vardhireddy Manorama , Vinod Kumar Khanna , Shamim Ahmad , Yogendra Kumar Jain , Chandra Shekhar
- Applicant: Sunkam Vanaja , Mandapati Jayalakshmi , Sunkara Sakunthala Madhavendra , Kaki Rajgopal , Mannepalli Lakshmi Kantam , Sunkara Vardhireddy Manorama , Vinod Kumar Khanna , Shamim Ahmad , Yogendra Kumar Jain , Chandra Shekhar
- Applicant Address: IN
- Assignee: Council of Scientific & Industual Research
- Current Assignee: Council of Scientific & Industual Research
- Current Assignee Address: IN
- Agency: Luedeka, Neely & Graham, P.C.
- Priority: IN898/DEL/2006 20060330
- Main IPC: G01N27/26
- IPC: G01N27/26
Abstract:
The present invention relates to the development of a biosensor to determine potassium in human blood serum using dibenzo-18-crown-6 (DB18C6) as ionophore. Human blood serum contains potassium in ppm levels i.e 137 to 200 mg/litre and sodium co exists with a 30 times higher concentration. Such a high concentration tends to interfere the selectivity towards potassium, but DB18C6 proves to have an excellent selectivity towards potassium and is highly sensitive to the lowest concentration of potassium levels present in the human blood serum. So the present invention reports the fabrication and characterization of ISFET (Ion Selective Field Effect transistor) coated with a monolayer of crown ether, dissolved in chloroform, on the gate of electrode.
Public/Granted literature
- US20070227886A1 BIOSENSOR TO DETERMINE POTASSIUM CONCENTRATION IN HUMAN BLOOD SERUM Public/Granted day:2007-10-04
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