Invention Grant
- Patent Title: Fragments of antibodies to epidermal growth factor receptor and methods of their use
- Patent Title (中): 抗体对表皮生长因子受体的片段及其使用方法
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Application No.: US11940322Application Date: 2007-11-14
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Publication No.: US07790164B2Publication Date: 2010-09-07
- Inventor: Boliang Cao
- Applicant: Boliang Cao
- Applicant Address: US MI Grand Rapids
- Assignee: Van Andel Research Institute
- Current Assignee: Van Andel Research Institute
- Current Assignee Address: US MI Grand Rapids
- Agency: Price, Heneveld, Cooper, DeWitt & Litton, LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; G01N33/53 ; C07K16/00
Abstract:
Antibody Fab fragments specific for the EGF receptor are disclosed, as are compositions and kits comprising these Fab proteins. The Fab proteins may be conjugated to drugs or other therapeutic agents or to diagnostic agents. Also disclosed are methods for diagnosing and treating diseases such as tumors and cancer in which cells express high levels of the EGFR, using the foregoing Fab molecules and conjugates.
Public/Granted literature
- US20080131373A1 FRAGMENTS OF ANTIBODIES TO EPIDERMAL GROWTH FACTOR RECEPTOR AND METHODS OF THEIR USE Public/Granted day:2008-06-05
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