Invention Grant
- Patent Title: Preparation of human, humanized or chimaeric antibodies or polypeptides having different binding profiles to Fcgamma receptors
- Patent Title (中): 制备与Fcγ受体具有不同结合特征的人，人源化或嵌合抗体或多肽
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Application No.: US10551819Application Date: 2004-04-05
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Publication No.: US07790399B2Publication Date: 2010-09-07
- Inventor: Dominique Bourel , Christophe De Romeuf , Sophie Siberil , Wolf Herman Fridman , Jean-Luc Teillaud , Nicolas Bihoreau , Emmanuel Nony
- Applicant: Dominique Bourel , Christophe De Romeuf , Sophie Siberil , Wolf Herman Fridman , Jean-Luc Teillaud , Nicolas Bihoreau , Emmanuel Nony
- Applicant Address: FR Les Ulis FR Paris
- Assignee: Laboratoire Francais du Fractionnement et des Biotechnolgies (LFB),Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee: Laboratoire Francais du Fractionnement et des Biotechnolgies (LFB),Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee Address: FR Les Ulis FR Paris
- Agency: Foley & Lardner LLP
- Priority: EP03290834 20030403
- International Application: PCT/IB2004/001390 WO 20040405
- International Announcement: WO2004/087757 WO 20041014
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
The present invention relates to a method for the production and the selection of human or chimæric or humanized antibodies or molecules that comprise the Fc region of human IgG, capable of modulating the activity of one or several particular Fc receptors, such as the triggering of inhibitory functions through the human type IIB receptors of IgG (FcgammaRIIB/CD32).
Public/Granted literature
- US20070135621A1 Therapeutic products with enhance ability to immunomodulate cell functions Public/Granted day:2007-06-14
Information query
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