Invention Grant
- Patent Title: Sesquiterpene synthases and methods of their use
- Patent Title (中): 倍半萜合酶及其使用方法
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Application No.: US11914536Application Date: 2006-06-08
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Publication No.: US07790413B2Publication Date: 2010-09-07
- Inventor: Michel Schalk
- Applicant: Michel Schalk
- Applicant Address: CH Geneva
- Assignee: Firmenich SA
- Current Assignee: Firmenich SA
- Current Assignee Address: CH Geneva
- Agency: Winston & Strawn LLP
- Priority: EP05105381 20050617
- International Application: PCT/IB2006/051831 WO 20060608
- International Announcement: WO2006/134523 WO 20061221
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C12P7/64 ; C12N9/00 ; C12N9/88 ; C12N1/20 ; C07H21/04 ; C12N15/82
Abstract:
The present invention relates to terpene synthases that are capable of synthesizing mono-, bi- and/or tri-cyclic sesquiterpenes having a C2-C7 or a C3-C7 bond, starting from an acyclic pyrophosphate terpene precursor, farnesyl- pyrophosphate. Accordingly, for the first time, sesquiterpene synthases catalyzing the cyclization to the santalene and bergamotene carbon skeleton are disclosed. The present invention further relates to nucleic acid sequences encoding the sesquiterpene synthases and to methods for making terpenoids.
Public/Granted literature
- US20080268500A1 Novel Sesquiterpene Synthases and Methods of their Use Public/Granted day:2008-10-30
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