Invention Grant
- Patent Title: Method for determining protein solubility
- Patent Title (中): 测定蛋白质溶解度的方法
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Application No.: US11700820Application Date: 2007-02-01
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Publication No.: US07790420B2Publication Date: 2010-09-07
- Inventor: Darren Hart , Franck Tarendeau
- Applicant: Darren Hart , Franck Tarendeau
- Applicant Address: DE Heidelburg
- Assignee: European Molecular Biology Laboratory
- Current Assignee: European Molecular Biology Laboratory
- Current Assignee Address: DE Heidelburg
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: GB0419628.3 20040903
- Main IPC: C12N15/64
- IPC: C12N15/64 ; C12N15/74 ; C12P21/06 ; C40B50/06

Abstract:
The present invention relates to methods of screening for expression of a soluble candidate protein within an expression library of candidate proteins. The method involves fusing each candidate protein in the library to a peptide substrate and identifying cells that express soluble candidate protein by detecting enzymatic modification of the peptide substrate.
Public/Granted literature
- US20070224618A1 Method for determining protein solubility Public/Granted day:2007-09-27
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