Invention Grant
US07790436B2 Method for production of (1S)-3-chloro-1-(2-thienyl)-propan-1-ol using alcohol dehydrogenase from thermoanaerobacter
有权
使用嗜热酵母杆菌醇脱氢酶生产（1S）-3-氯-1-（2-噻吩基） - 丙-1-醇的方法
- Patent Title: Method for production of (1S)-3-chloro-1-(2-thienyl)-propan-1-ol using alcohol dehydrogenase from thermoanaerobacter
- Patent Title (中): 使用嗜热酵母杆菌醇脱氢酶生产（1S）-3-氯-1-（2-噻吩基） - 丙-1-醇的方法
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Application No.: US12158526Application Date: 2006-12-13
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Publication No.: US07790436B2Publication Date: 2010-09-07
- Inventor: Michael Breuer
- Applicant: Michael Breuer
- Applicant Address: DE Ludwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Ludwigshafen
- Agency: Connolly Bove Lodge & Hutz LLP
- Priority: DE102005062661 20051223
- International Application: PCT/EP2006/069629 WO 20061213
- International Announcement: WO2007/074060 WO 20070705
- Main IPC: C12P41/00
- IPC: C12P41/00
Abstract:
A process for preparing optically active (1S)-3-chloro-1-(2-thienyl)propan-1-ol of the formula I by, in a medium comprising 3-chloro-1-(2-thienyl)propan-1-one of the formula II reducing this compound to the compound of the formula I by means of an alcohol dehydrogenase from the Thermoanaerobacter genus, and isolating the product formed in substantially enantiomerically pure form.
Public/Granted literature
- US20080319208A1 Method for Production of Optically Active (1S)-3-Chloro-1-(2-Thienyl)-Propan-1-Ol Public/Granted day:2008-12-25
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