Invention Grant
US07790697B2 Compositions and methods for inhibiting the synthesis or expression of MMP-1
有权
用于抑制MMP-1的合成或表达的组合物和方法
- Patent Title: Compositions and methods for inhibiting the synthesis or expression of MMP-1
- Patent Title (中): 用于抑制MMP-1的合成或表达的组合物和方法
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Application No.: US12352214Application Date: 2009-01-12
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Publication No.: US07790697B2Publication Date: 2010-09-07
- Inventor: Colby Wyatt , Constance F. Brinckerhoff
- Applicant: Colby Wyatt , Constance F. Brinckerhoff
- Applicant Address: US NH Hanover
- Assignee: Trustees of Dartmouth College
- Current Assignee: Trustees of Dartmouth College
- Current Assignee Address: US NH Hanover
- Agency: Licata & Tyrrell P.C.
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/04
Abstract:
The present invention relates to the specific inhibition of matrix metalloproteinase 1 (MMP-1) using agents which inhibit the synthesis or expression of MMP-1. Such agents are useful for suppressing invasion or metastasis of a tumor cell and in the treatment, prevention and management of cancer.
Public/Granted literature
- US20090270487A1 Compositions and methods for inhibiting the synthesis or expression of MMP-1 Public/Granted day:2009-10-29
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