Imidazopyridine derivatives useful as iNOS inhibitors

Invention Grant

US07790710B2 Imidazopyridine derivatives useful as iNOS inhibitors 失效

Title translation: 可用作iNOS抑制剂的咪唑并吡啶衍生物

Patent Title: Imidazopyridine derivatives useful as iNOS inhibitors
Patent Title (中): 可用作iNOS抑制剂的咪唑并吡啶衍生物
Application No.: US11886785

Application Date: 2006-03-29
Publication No.: US07790710B2

Publication Date: 2010-09-07
Inventor: Thomas Fuchss , Andreas Strub , Wolf-Rüdiger Ulrich , Christian Hesslinger , Martin Lehner , Raimund Külzer , Rainer Boer , Manfrid Eltze
Applicant: Thomas Fuchss , Andreas Strub , Wolf-Rüdiger Ulrich , Christian Hesslinger , Martin Lehner , Raimund Külzer , Rainer Boer , Manfrid Eltze
Applicant Address: DE Constance
Assignee: NYCOMED GmbH
Current Assignee: NYCOMED GmbH
Current Assignee Address: DE Constance
Agency: The Nath Law Group
Agent Joshua B. Goldberg; Sheldon M. McGee
Priority: EP05102558 20050331
International Application: PCT/EP2006/061141 WO 20060329
International Announcement: WO2006/103255 WO 20061005
Main IPC: A01N43/00
IPC: A01N43/00 ; A61K31/55 ; A01N43/46 ; A01N43/90 ; A61K31/519 ; C07D413/00 ; C07D415/00 ; C07D417/00 ; C07D419/00 ; C07D513/02 ; C07D515/02 ; C07D403/02

Abstract:

The compounds of formula (I) in which R1, R11 and A have the meanings as given in the description are novel effective iNOS inhibitors.

Abstract(Chinese):

其中R1，R11和A具有如本说明书中给出的含义的式（I）化合物是新的有效的iNOS抑制剂。

Public/Granted literature

Information query

Espacenet

IPC分类:

A	人类生活必需
A01	农业；林业；畜牧业；狩猎；诱捕；捕鱼
A01N	人体、动植物体或其局部的保存（食品或粮食的保存入A23）；杀生剂，例如作为消毒剂，作为农药或作为除草剂（杀灭或防止不期望生物体的生长或繁殖的医用、牙科用或梳妆用的配制品入A61K）；害虫驱避剂或引诱剂；植物生长调节剂
A01N43/00	含有杂环化合物的杀生剂、害虫驱避剂或引诱剂，或植物生长调节剂（含有环酐，环状亚胺的化合物入A01N37/00；含有分子式Xm……CnNCC的化合物，即仅含1个杂环，其中m≥1和n≥0及NCC是未取代的或是烷基取代的吡咯烷、哌啶、吗啉、硫代吗啉、哌嗪或带有4个或更多CH2基的聚亚甲基亚胺的化合物入A01N33/00至A01N41/12；含环丙烷羧酸或其衍生物，如具有杂环的酯入A01N53/00）