Invention Grant
- Patent Title: Modulators of melanocortin receptor
- Patent Title (中): 黑皮质素受体的调节剂
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Application No.: US11878708Application Date: 2007-07-26
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Publication No.: US07790719B2Publication Date: 2010-09-07
- Inventor: Tricia J. Vos , Michael Patane , Michael E. Solomon , Christopher Blackburn , Mihaela D. Danca
- Applicant: Tricia J. Vos , Michael Patane , Michael E. Solomon , Christopher Blackburn , Mihaela D. Danca
- Applicant Address: US MA Cambridge
- Assignee: Ore Pharmaceuticals, Inc.
- Current Assignee: Ore Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Harness, Dickey & Pierce, P.L.C.
- Agent J. Timothy Keane; Kisuk Lee
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61K31/535 ; A61K31/517 ; A61K31/445 ; C07D239/02 ; C07D233/88 ; C07D413/14 ; C07D239/70
Abstract:
This invention provides compounds and methods for treating melanocortin receptor associated disorders, such as weight loss disorders including cachexia resulting from cancer and other chronic illnesses. The compounds are represented by formula I: wherein X is oxygen or sulfur; G is G1 or G2: L1, L2, L3 and Q are linker groups, and Rings A, B and C, and R1-R14 are described in the specification. The compounds are antagonists of melanocortin receptors.
Public/Granted literature
- US20070293498A1 Modulators of melanocortin receptor Public/Granted day:2007-12-20
Information query
