Invention Grant
- Patent Title: Tyrosine kinase inhibitors
- Patent Title (中): 酪氨酸激酶抑制剂
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Application No.: US12083745Application Date: 2006-10-18
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Publication No.: US07790739B2Publication Date: 2010-09-07
- Inventor: Jongwon Lim , Ana Esther Gabarda Ortega
- Applicant: Jongwon Lim , Ana Esther Gabarda Ortega
- Applicant Address: US NJ Rahway
- Assignee: Merck & Co., Inc. and Merck Sharp & Dohme Corp.
- Current Assignee: Merck & Co., Inc. and Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent David A. Muthard
- International Application: PCT/US2006/040664 WO 20061018
- International Announcement: WO2007/050380 WO 20070503
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D455/04 ; C07D413/00
Abstract:
The present invention relates to imidazo[1,2-a]pyrimidine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
Public/Granted literature
- US20090247565A1 Tyrosine Kinase Inhibitors Public/Granted day:2009-10-01
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