Invention Grant
- Patent Title: Substituted phenyl methanone derivatives
- Patent Title (中): 取代苯甲酮衍生物
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Application No.: US11332999Application Date: 2006-01-17
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Publication No.: US07790763B2Publication Date: 2010-09-07
- Inventor: Synese Jolidon , Robert Narquizian , Roger David Norcross , Emmanuel Pinard
- Applicant: Synese Jolidon , Robert Narquizian , Roger David Norcross , Emmanuel Pinard
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Priority: EP05100280 20050118
- Main IPC: A61K31/40
- IPC: A61K31/40 ; C07D295/27
Abstract:
The present invention relates to compounds of formula I wherein R1, R2, R3, n, and m, are as defined in the specification and to pharmaceutically acceptable acid addition salts thereof. These compounds are good inhibitors of the glycine transporter 1 (GlyT-1) and are useful for the treatment of CNS disorders such as schizophrenia, cognitive impairment, and Alzheimer's disease.
Public/Granted literature
- US20060160788A1 Substituted phenyl methanone derivatives Public/Granted day:2006-07-20
Information query
