Invention Grant
US07790863B2 Angiogenesis inhibiting molecules and their use in the treatment and diagnosis of cancer
有权
血管生成抑制分子及其在治疗和诊断癌症中的应用
- Patent Title: Angiogenesis inhibiting molecules and their use in the treatment and diagnosis of cancer
- Patent Title (中): 血管生成抑制分子及其在治疗和诊断癌症中的应用
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Application No.: US10579105Application Date: 2004-11-19
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Publication No.: US07790863B2Publication Date: 2010-09-07
- Inventor: Beat A. Imhof , Michel Aurrand-Lions
- Applicant: Beat A. Imhof , Michel Aurrand-Lions
- Applicant Address: CH Coinsins, Vaud
- Assignee: Merck Serono S.A.
- Current Assignee: Merck Serono S.A.
- Current Assignee Address: CH Coinsins, Vaud
- Agency: Saliwanchik, Lloyd & Saliwanchik
- Priority: EP03026629 20031119
- International Application: PCT/EP2004/013247 WO 20041119
- International Announcement: WO2005/050213 WO 20050602
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; G01N33/53 ; G01N33/577 ; C12P21/08 ; C12N5/20
Abstract:
The present invention relates to angiogenesis inhibiting molecules that are the monoclonal antibody H33 or fragments or derivatives thereof, to their use in the treatment of cancer, in particular the treatment of solid tumors and to therapeutic and diagnostic compositions comprising them. The invention relates in particular to humanized derivatives of H33 of human monoclonal antibodies having the specificity of H33.
Public/Granted literature
- US20070202110A1 Angiogenesis Inhibiting Molecules And Their Use In The Treatment And Diagnosis Of Cancer Public/Granted day:2007-08-30
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