Invention Grant
- Patent Title: Antisense oligonucleotides with increased RNase sensitivity
- Patent Title (中): 具有增加的RNA酶敏感性的反义寡核苷酸
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Application No.: US10142566Application Date: 2002-05-08
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Publication No.: US07790877B2Publication Date: 2010-09-07
- Inventor: Timothy A. Riley , Bob D. Brown , Lyle J. Arnold
- Applicant: Timothy A. Riley , Bob D. Brown , Lyle J. Arnold
- Applicant Address: US CA San Diego
- Assignee: Gen-Probe, Incorporated
- Current Assignee: Gen-Probe, Incorporated
- Current Assignee Address: US CA San Diego
- Agency: Foley & Lardner LLP
- Main IPC: C07H21/04
- IPC: C07H21/04
Abstract:
Combinatorial libraries comprise first oligonucleotide analogs and second oligonucleotide analogs which are coupled together to form antisense molecules capable of binding target polynucleotides and activating an RNase, and ribozymes capable of cleaving polynucleotides.
Public/Granted literature
- US20030119016A1 Antisense oligonucleotides with increased RNase sensitivity Public/Granted day:2003-06-26
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