Invention Grant
- Patent Title: Process for production of optically active PPAR-activating compound and intermediate of the same
- Patent Title (中): 光学活性PPAR活化化合物及其中间体的制备方法
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Application No.: US11816472Application Date: 2006-02-23
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Publication No.: US07790903B2Publication Date: 2010-09-07
- Inventor: Yukiyoshi Yamazaki , Takaaki Araki , Minoru Koura , Kimiyuki Shibuya
- Applicant: Yukiyoshi Yamazaki , Takaaki Araki , Minoru Koura , Kimiyuki Shibuya
- Applicant Address: JP Nagoya-shi
- Assignee: Kowa Co., Ltd.
- Current Assignee: Kowa Co., Ltd.
- Current Assignee Address: JP Nagoya-shi
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2005-047476 20050223
- International Application: PCT/JP2006/303245 WO 20060223
- International Announcement: WO2006/090768 WO 20060831
- Main IPC: C07D263/58
- IPC: C07D263/58
Abstract:
A process for obtaining a compound (1) and an intermediate thereof in high yield and high optical yield is provided.A process for producing a compound (4), the process including reacting a compound (2) with a compound (3) in the presence of a base; and a process for producing a compound (1), the process including reacting a compound (2) with a compound (3) in the presence of a base to yield a compound (4) and then deesterifying the compound (4). wherein R represents an alkyl group having 1 to 6 carbon atoms or an aralkyl group having 7 to 8 carbon atoms.
Public/Granted literature
- US20080194833A1 Process For Production of Optically Active Ppar-Activating Compound and Intermediate of the Same Public/Granted day:2008-08-14
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