A wound dressing having a suction member adaptable for connection to a source of vacuum pressure. The wound dressing preferably has a hydrophobic or biodegradable base layer and one or more absorptive layers for absorbing fluid from the wound. The absorptive layers are preferably quilted with patches containing desiccant, adsorbent, or absorbent material. Alternatively, the wound dressing may allow fluid to pass through the suction member. A semi-permeable cover is provided for allowing the wound to breathe while protecting the wound from undesirable substances such as bacteria, viruses, or fluids. The cover may have a bladder for distributing contact pressure away from the wound. Various sensors may be provided in the wound dressing for sensing various physiological parameters in the wound, such as oxygen saturation, blood pressure, respiratory rate, blood glucose, and serous fluid turbidity. Medicine may also be applied to the wound through the wound dressing.