Invention Grant
- Patent Title: Methods to predict the outcome of treatment with antidepressant medication
- Patent Title (中): 预防抗抑郁药物治疗结果的方法
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Application No.: US12051494Application Date: 2008-03-19
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Publication No.: US07795033B2Publication Date: 2010-09-14
- Inventor: Francis J. McMahon , Gonzalo E. Laje , Silvia Paddock , Husseini K. Manji , A. John Rush , Alexander F. Wilson
- Applicant: Francis J. McMahon , Gonzalo E. Laje , Silvia Paddock , Husseini K. Manji , A. John Rush , Alexander F. Wilson
- Applicant Address: US DC Washington US TX Austin
- Assignee: The United States of America as represented by the Department of Health and Human Services,Board of Regents, The University of Texas System
- Current Assignee: The United States of America as represented by the Department of Health and Human Services,Board of Regents, The University of Texas System
- Current Assignee Address: US DC Washington US TX Austin
- Agency: Leydig, Voit & Mayer
- Main IPC: G01N33/50
- IPC: G01N33/50 ; C12Q1/68
Abstract:
The invention provides a method for determining the outcome of treatment with an antidepressant medication in a patient. In particular, the invention provides a method of screening patients to identify those patients with a decreased risk of non-response to treatment with antidepressant medication by obtaining a sample of genetic material from the patients, and then assaying the sample for the presence of a genotype which is associated with a decreased risk of non-response to treatment with antidepressant medication. The genotype is characterized by a polymorphism in the genes HTR2A, GRIK4, BCL2, and a combination thereof.
Public/Granted literature
- US20080233657A1 METHODS TO PREDICT THE OUTCOME OF TREATMENT WITH ANTIDEPRESSANT MEDICATION Public/Granted day:2008-09-25
Information query
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