Invention Grant
US07795202B2 Methods for treating a neurological disorder by peripheral administration of a transforming growth factor alpha (TGF-a)
有权
通过外周施用转化生长因子α（TGF-α）治疗神经障碍的方法
- Patent Title: Methods for treating a neurological disorder by peripheral administration of a transforming growth factor alpha (TGF-a)
- Patent Title (中): 通过外周施用转化生长因子α（TGF-α）治疗神经障碍的方法
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Application No.: US10167384Application Date: 2002-06-10
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Publication No.: US07795202B2Publication Date: 2010-09-14
- Inventor: James H. Fallon , Richard M. Kinyamu
- Applicant: James H. Fallon , Richard M. Kinyamu
- Applicant Address: US CA San Francisco
- Assignee: Neurorepair, Inc.
- Current Assignee: Neurorepair, Inc.
- Current Assignee Address: US CA San Francisco
- Agency: Ropes & Gray LLP
- Agent James F. Haley, Jr.
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C12N5/00 ; C12N5/07 ; C12N5/079 ; C12N5/0793 ; C12N5/0797 ; A61K49/00 ; C07K14/00
Abstract:
The invention provides methods of treating a subject having a disease, disorder or condition of the central nervous system. The methods include administering TGF-α polypeptides, related polypeptides, fragments and mimetics thereof useful in stimulating progenitor cell or stem cell proliferation, migration and differentiation. The methods of the invention are useful to treat and prophylactically ameliorate neurological tissue injury in vivo.
Public/Granted literature
- US20030036193A1 Methods for treating a neurological disorder by peripheral administration of a trophic factor Public/Granted day:2003-02-20
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