Invention Grant
US07795265B2 Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators
有权
取代咪唑4-甲酰胺作为胆囊收缩素-1受体调节剂
- Patent Title: Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators
- Patent Title (中): 取代咪唑4-甲酰胺作为胆囊收缩素-1受体调节剂
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Application No.: US12225906Application Date: 2007-04-10
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Publication No.: US07795265B2Publication Date: 2010-09-14
- Inventor: Richard Berger , Scott Edmondson , Alexa Hansen , Cheng Zhu
- Applicant: Richard Berger , Scott Edmondson , Alexa Hansen , Cheng Zhu
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Baerbel R. Brown; John C. Todaro
- International Application: PCT/US2007/008832 WO 20070410
- International Announcement: WO2007/120655 WO 20071025
- Main IPC: A61K31/4178
- IPC: A61K31/4178 ; A61K31/454 ; A61K316/496 ; C07D233/94 ; C07D403/04 ; C07D405/04
Abstract:
Certain novel substituted imidazole 4-carboxamides are ligands of the human cholecystokinin receptor and, in particular, are selective ligands of the human cholecystokinin-1 receptor (CCK-1R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of CCK-1R, such as obesity, and diabetes.
Public/Granted literature
- US20090118300A1 Substituted Imidazole 4-Carboxamides as Cholecystokinin-1 Receptor Modulators Public/Granted day:2009-05-07
Information query
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