Invention Grant
US07795278B2 Substituted tetrahydro-2H-isoquinolin-1-one derivatives, and methods for the production and use thereof
失效
取代的四氢-2H-异喹啉-1-酮衍生物及其制备和使用方法
- Patent Title: Substituted tetrahydro-2H-isoquinolin-1-one derivatives, and methods for the production and use thereof
- Patent Title (中): 取代的四氢-2H-异喹啉-1-酮衍生物及其制备和使用方法
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Application No.: US11567352Application Date: 2006-12-06
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Publication No.: US07795278B2Publication Date: 2010-09-14
- Inventor: Stefan Peukert , Stefan Guessregen , Armin Hofmeister , Herman Schreuder , Uwe Schwahn
- Applicant: Stefan Peukert , Stefan Guessregen , Armin Hofmeister , Herman Schreuder , Uwe Schwahn
- Applicant Address: US DE Frankfurt am Main
- Assignee: sanofi-aventis Deutschland GmbH
- Current Assignee: sanofi-aventis Deutschland GmbH
- Current Assignee Address: US DE Frankfurt am Main
- Agent Serena Farquharson-Torres
- Priority: DE102004028973 20040616
- Main IPC: C07D217/22
- IPC: C07D217/22 ; A61K31/47
Abstract:
This invention relates to compounds according to the general formula (I), where the definitions of the substituents R1, R2, Ar and X are as specified in the description, and to their physiologically tolerated salts, methods for the preparation of these compounds and their use as medicaments. These compounds are poly(ADP-ribose) polymerase (PARP) inhibitors.
Public/Granted literature
- US20070142430A1 SUBSTITUTED TETRAHYDRO-2H-ISOQUINOLIN-1-ONE DERIVATIVES, AND METHODS FOR THE PRODUCTION AND USE THEREOF Public/Granted day:2007-06-21
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