Invention Grant
- Patent Title: PC5 as a factor IX propeptide processing enzyme
- Patent Title (中): PC5作为因子IX前肽加工酶
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Application No.: US12489391Application Date: 2009-06-22
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Publication No.: US07795400B2Publication Date: 2010-09-14
- Inventor: Robert T. Peters , Alan J. Bitonti
- Applicant: Robert T. Peters , Alan J. Bitonti
- Applicant Address: US MA Waltham
- Assignee: Syntonix Pharmaceuticals, Inc.
- Current Assignee: Syntonix Pharmaceuticals, Inc.
- Current Assignee Address: US MA Waltham
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K38/48
- IPC: A61K38/48 ; C12Q1/00 ; C12N9/00
Abstract:
Compositions and methods for preparing Factor IX, Factor IX-containing fusion proteins, and Factor IX-containing conjugates with processing of Factor IX propeptide by PC5, are provided. In one embodiment PC5 is used to process a precursor polypeptide for a Factor IX-Fc monomer-dimer hybrid.
Public/Granted literature
- US20100015659A1 PC5 as a Factor IX Propeptide Processing Enzyme Public/Granted day:2010-01-21
Information query
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