Invention Grant
US07795445B2 Substituted 2-aminoalkylthiobenzimidazole compounds, pharmaceutical compositions thereof and methods for their use
有权
取代的2-氨基烷硫基苯并咪唑化合物，其药物组合物及其使用方法
- Patent Title: Substituted 2-aminoalkylthiobenzimidazole compounds, pharmaceutical compositions thereof and methods for their use
- Patent Title (中): 取代的2-氨基烷硫基苯并咪唑化合物，其药物组合物及其使用方法
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Application No.: US11855221Application Date: 2007-09-14
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Publication No.: US07795445B2Publication Date: 2010-09-14
- Inventor: Elisabeth Defossa , Karl Schoenafinger , Gerhard Jaehne , Christian Buning , Georg Tschank , Ulrich Werner
- Applicant: Elisabeth Defossa , Karl Schoenafinger , Gerhard Jaehne , Christian Buning , Georg Tschank , Ulrich Werner
- Applicant Address: FR Paris
- Assignee: sanofi-aventis
- Current Assignee: sanofi-aventis
- Current Assignee Address: FR Paris
- Agent Serena Farquharson-Torres
- Priority: DE102005017605 20050416
- Main IPC: A61K31/4184
- IPC: A61K31/4184 ; C07D235/28
Abstract:
The present invention comprises the substituted 2-aminoalkylthiobenzimidazoles of formula I wherein R1-R5 and R11-R16 are hereinafter defined. These compounds, their derivatives and the pharmaceutically acceptable salts thereof are useful in the reduction of elevated blood sugar levels and are therefore useful in the treatment of hyperglycemia, diabetes, atherosclerosis and other blood sugar disorders. These compounds are particularly suitable in the treatment of type-2 diabetes.
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