In one embodiment, there is provided a method for producing a sterilized and pyrogen-free bag for storing fluids. The method includes providing a bag comprised of polymeric film and heating the bag to at least approximately 253 degrees Celsius for at least approximately 30 minutes for sterilization and pyrogen removal. The polymeric film is a polymer selected from the group of poly(oxy-1,4-phenylene-oxy -1,4-phenylene-carbonyl-1,4-phenylene) (PEEK); polytetrafluoroethylene (PTFE); a perfluoroalkoxy (PFA) polymer; poly(tetrafluoroethylene-co-perfluoromethyl vinyl ether) (MFA); polyperfluoro(ethylene-co-propylene)(FEP); poly(ethylene-alt-chlorotrifluoroethylene) (ECTFE); poly(ethylene-co-tetrafluoroethylene) (ETFE); poly(vinylidene fluoride) (PDVF); tetrafluoroethylene-co-hexafluoropropylene-co-vinylidene fluoride terpolymer (THV); poly(bisphenol A-co-4-nitrophthalic anhydride-co-1,3-phenylenediamine) (PEI); poly(4-methyl-1-pentene) (PMP); and suitable mixtures thereof.