Invention Grant
- Patent Title: Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
- Patent Title (中): 基于增加结晶微粒表面对活性剂的亲和力的药物制剂的方法
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Application No.: US11532063Application Date: 2006-09-14
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Publication No.: US07799344B2Publication Date: 2010-09-21
- Inventor: Keith A. Oberg
- Applicant: Keith A. Oberg
- Applicant Address: US CA Valencia
- Assignee: MannKind Corporation
- Current Assignee: MannKind Corporation
- Current Assignee Address: US CA Valencia
- Agency: K&L Gates LLP
- Agent Louis C. Cullman; Michelle Glasky Bergman
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/28 ; A61K38/28

Abstract:
Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Type of surface properties that are altered by the disclosed methods include by electrostatic properties, hydrophobic properties and hydrogen bonding properties.
Public/Granted literature
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