Invention Grant
US07799540B2 Method of producing lycopene through the fermentation of selected strains of Blackeslea trispora, formulations and uses of the lycopene thus obtained
有权
通过发酵选择的三倍体黑三烯菌株产生番茄红素的方法，由此获得的番茄红素的制剂和用途
- Patent Title: Method of producing lycopene through the fermentation of selected strains of Blackeslea trispora, formulations and uses of the lycopene thus obtained
- Patent Title (中): 通过发酵选择的三倍体黑三烯菌株产生番茄红素的方法，由此获得的番茄红素的制剂和用途
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Application No.: US10498682Application Date: 2002-12-20
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Publication No.: US07799540B2Publication Date: 2010-09-21
- Inventor: Ana Teresa Marcos Rodríguez , Antonio Estrella De Castro , Javier Costa Perez , Manuel Antonio Oliver Ruiz , Nieves Fraile Yecora , Juan Luis De La Fuente Moreno , Marta Rodríguez Saiz , Bruno Diez Garcia , Enrieque Peiro Cezon , Angel Muñoz Ruiz , Walter Cabri , Juan Francisco Lopez Ortiz , José Luis Barredo Fuente
- Applicant: Ana Teresa Marcos Rodríguez , Antonio Estrella De Castro , Javier Costa Perez , Manuel Antonio Oliver Ruiz , Nieves Fraile Yecora , Juan Luis De La Fuente Moreno , Marta Rodríguez Saiz , Bruno Diez Garcia , Enrieque Peiro Cezon , Angel Muñoz Ruiz , Walter Cabri , Juan Francisco Lopez Ortiz , José Luis Barredo Fuente
- Applicant Address: ES Leon
- Assignee: Vitatene, S.A.
- Current Assignee: Vitatene, S.A.
- Current Assignee Address: ES Leon
- Agency: Ladas and Parry LLP
- Priority: ES200102925 20011231
- International Application: PCT/ES02/00610 WO 20021220
- International Announcement: WO03/056028 WO 20030710
- Main IPC: C12P23/00
- IPC: C12P23/00 ; C12P5/00 ; C07C403/00
Abstract:
The method of fermentation with selected strains of B. trispora described in the present invention makes it possible to achieve lycopene yields higher than those currently described. The methods of isolation, purification and formulation are applicable to any natural source of lycopene, especially to submerged cultures of mucoral fungi of the genera Blakeslea, Choanephora, Phycomyces or Mucor. The method of extraction makes it possible to simplify the recovery process and increase the purity of the product, relative to the methods previously described. The methods of formulation provide high added value, since they make it possible to obtain stabilized preparations of lycopene for direct application in the food and pharmaceutical fields.
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